Open AccessContribution of C3d-P28 repeats to enhancement of immune responses against HBV-preS2/S induced by gene immunization
Author(s) -
Lixin Wang,
Wenju Xu,
Qingdong Guan,
Yiwei Chu,
Ying Wang,
Sidong Xiong
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i14.2072
Subject(s) - biology , microbiology and biotechnology , virology , hbsag , immunogenicity , antibody , immune system , plasmid , gene , hepatitis b virus , immunology , virus , genetics
To investigate whether P28 derived from C3d can enhance the immune response to HBV-preS2/S induced by directly injection of naked plasmids containing variable repeats of P28 and HBV-preS2/S in fusion form.