Open AccessCytomegalovirus and chronic allograft rejection in liver transplantation
Author(s) -
Gao Ling,
Shusen Zheng
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i13.1857
Subject(s) - cytomegalovirus , liver transplantation , medicine , immunology , transplantation , cytomegalovirus infection , human cytomegalovirus , chronic infection , cytomegalovirus infections , virus , viral disease , herpesviridae , immune system
Cytomegalovirus (CMV) remains one of the most frequent viral infections and the most common cause of death after liver transplantation (LT). Chronic allograft liver rejection remains the major obstacle to long-term allograft survival and CMV infection is one of the suggested risk factors for chronic allograft rejection. The precise relationship between cytomegalovirus and chronic rejection remains uncertain. This review addresses the morbidity of cytomegalovirus infection and the risk factors associated with it, the relationship between cytomegalovirus and chronic allograft liver rejection and the potential mechanisms of it.