Open AccessEffects of tegaserod on Fos, substance P and calcitonin gene-related peptide expression induced by colon inflammation in lumbarsacral spinal cord
Author(s) -
Yihan Sun,
Jintai Luo
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i12.1830
Subject(s) - calcitonin gene related peptide , spinal cord , tegaserod , substance p , agonist , medicine , calcitonin , endocrinology , neuropeptide , anesthesia , chemistry , pharmacology , receptor , constipation , psychiatry
To investigate the mechanisms of tegaserod, a partial 5-HT4 agonist, in reducing visceral sensitivity by observing Fos, substance P (SP) and calcitonin gene-related peptide (CGRP) expression in the lumbarsacral spinal cord induced by colonic inflammation in rats.