Open AccessSuperantigen-SEA gene modified tumor vaccine for hepatocellular carcinoma: Anin vitrostudy
Author(s) -
Shao-Ying Lu,
Yan-Fang Sui,
Zengshan Li,
Jing Ye,
Hailong Dong,
Ping Qü,
Xiumin Zhang,
Wenyong Wang,
Yu-Song Li
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i1.53
Subject(s) - microbiology and biotechnology , elispot , biology , plasmid , virology , t cell , gene , immune system , immunology , biochemistry
To construct an eukaryotic superantigen gene expression vector containing the recombinant gene of SEA and CD80 molecule transmembrane region (CD80TM), and to express staphylococcus enterotoxin A (SEA) on the membrane of hepatocellular carcinoma (HCC) cell to form a superantigen gene modified tumor vaccine for HCC.