Open AccessSeparate basolateral and apical phosphatidylcholinesecretion routes in intestinally differentiated tumor cells
Author(s) -
Daniel Gotthardt,
Annika Braun,
Anke Tietje,
Karl Heinz Weiss,
Robert Ehehalt,
Wolfgang Stremmel
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.5821
Subject(s) - secretion , apical membrane , compartment (ship) , apical cell , epithelial polarity , sphingomyelin , mucus , epithelium , biology , microbiology and biotechnology , cell culture , chemistry , medicine , cell , endocrinology , biochemistry , membrane , ecology , oceanography , geology , genetics
To investigate whether the secretion of phosphatidylcholine (PC) in intestinal mucus occurs by apical secretion or via basolateral excretion and to determine its subsequent passage across the tight junctions to the apical mucus.