Open AccessStable knockdown of heparanase expression in gastriccancer cells in vitro
Author(s) -
Liduan Zheng,
Guosong Jiang,
Jiarui Pu,
Mei Hong,
Jing Dong,
Xiaohua Hou,
Qiangsong Tong
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.5442
Subject(s) - heparanase , small hairpin rna , gene knockdown , angiogenesis , transfection , matrigel , microbiology and biotechnology , gentamicin protection assay , cancer cell , cell growth , cancer research , cell culture , mtt assay , biology , metastasis , chemistry , cancer , biochemistry , genetics
To develop short hairpin RNA (shRNA) against heparanase, and to determine its effects on heparanase expression and the malignant characteristics of gastric cancer cells.