Open AccessEmodin protects rat liver from CCl4-induced fibrogenesis via inhibition of hepatic stellate cells activation
Author(s) -
Miaoxian Dong,
Jia Yan,
Yingbo Zhang,
Chengchong Li,
Yutao Geng,
Li Zhou,
Xueyan Li,
Jicheng Liu,
Yingcai Niu
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.4753
Subject(s) - emodin , hydroxyproline , hepatic stellate cell , carbon tetrachloride , hepatic fibrosis , h&e stain , medicine , ccl4 , chemistry , fibrosis , endocrinology , staining , alanine transaminase , immunohistochemistry , pathology , biochemistry , organic chemistry
To investigate the role of emodin in protecting the liver against fibrogenesis caused by carbon tetrachloride (CCl(4)) in rats and to further explore the underlying mechanisms.