Open AccessEffects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action
Author(s) -
Huizhen Sun,
Juan Ren,
Qing Zhu,
Fan-Zhong Kong,
Lei Wu,
BoRong Pan
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.4547
Subject(s) - lysophosphatidic acid , cell migration , pi3k/akt/mtor pathway , ly294002 , protein kinase b , mapk/erk pathway , apoptosis , rhoa , cell growth , mek inhibitor , microbiology and biotechnology , cell adhesion , chemistry , cancer research , signal transduction , biology , cell , biochemistry , receptor
To study the effects of lysophosphatidic acid (LPA) on proliferation, adhesion, migration, and apoptosis in the human colon cancer cell line, SW480, and its mechanisms of action.