Open AccessInsulin-like growth factor binding protein-7 induces activation and transdifferentiation of hepatic stellate cells in vitro
Author(s) -
Lixin Liu,
Shuai Huang,
Qianqian Zhang,
Yi Liu,
Dongmei Zhang,
Xingyi Guo,
Dong Han
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.3246
Subject(s) - transdifferentiation , hepatic stellate cell , flow cytometry , immunocytochemistry , growth factor , transforming growth factor beta , biology , microbiology and biotechnology , fibronectin , blot , transforming growth factor , chemistry , endocrinology , stem cell , biochemistry , receptor , extracellular matrix , gene
To investigate the role of insulin-like growth factor binding protein-7 (IGFBP-7) in the activation and transdifferentiation of hepatic stellate cells (HSC) in vitro.