Open AccessSpecific activation of 2'-5'oligoadenylate synthetase gene promoter by hepatitis C virus-core protein: A potential for developing hepatitis C virus targeting gene therapy
Author(s) -
Ying Wang,
Shanshan Mao,
Qiaojun He,
Yuan Zi,
Ji Wen,
Daxiong Feng
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.3178
Subject(s) - transfection , microbiology and biotechnology , promoter , hepatitis c virus , plasmid , gene , biology , genetic enhancement , virology , luciferase , cell culture , virus , gene expression , genetics
To examine whether 2'-5'oligoadenylate synthetase (OAS) gene promoter can be specifically activated by hepatitis C virus (HCV)-core protein.