Open AccessA case of hepatic angiomyolipoma difficult to distinguish from hepatocellular carcinoma
Author(s) -
Masakazu Takahara,
Yasuhiro Miyake,
Kazuyuki Matsumoto,
Daisuke Kawai,
Eisuke Kaji,
Tatsuya Toyokawa,
Morihito Nakatsu,
Masaharu Ando,
Mamoru Hirohata
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.2930
Subject(s) - angiomyolipoma , hepatocellular carcinoma , pathology , immunohistochemistry , medicine , magnetic resonance imaging , radiology , kidney
We report a case of hepatic angiomyolipoma with uncommon clinical features. A 56-year-old man presented with a hepatic tumor in the caudate lobe. The tumor was hypoechoic on ultrasonography, showed early-phase hyperattenuation on enhanced computed tomography and did not absorb iron on superparamagnetic iron oxide-enhanced magnetic resonance imaging. Hepatocellular carcinoma was highly suspected, and the patient underwent hepatic resection. Histologically, the tumor was mainly composed of smooth muscle cells and contained small amounts of adipose cells and blood vessels. On immunohistochemical staining, the smooth muscle cells were positive for a melanocytic cell-specific monoclonal antibody. In cases with uncommon features of angiomyolipoma, it is quite difficult to distinguish angiomyolipoma from hepatocellular carcinoma.