Open AccessSilencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice
Author(s) -
Jing Li,
Yun-Song Piao,
Zheng Jiang,
Li Chen,
Hongwei Sun
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.2602
Subject(s) - survivin , microbiology and biotechnology , stat protein , rna interference , gene silencing , stat3 , small interfering rna , tunel assay , biology , cancer research , terminal deoxynucleotidyl transferase , transfection , apoptosis , immunohistochemistry , cell culture , rna , gene , immunology , biochemistry , genetics
To explore the effect of silencing of signal transducer and activator of transcription 3 (STAT3) expression by RNA interference (RNAi) on growth of human hepatocellular carcinoma (HCC) in tumor-bearing nude mice in vivo.