Open AccessProtective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significanly correlated with cytochrome P450 suppression
Author(s) -
Xia Chen,
Changkai Sun,
Gia Hân,
Jinrong Peng,
Ying Li,
Yanxia Liu,
Yuanyuan Lv,
Kexin Liu,
Qin Zhou,
Huijun Sun
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.1829
Subject(s) - cyp1a2 , cyp2e1 , cytochrome p450 , acetaminophen , pharmacology , intraperitoneal injection , chemistry , blot , polyphenol , glutathione , antioxidant , cyp3a4 , medicine , endocrinology , enzyme , biochemistry , gene
To investigate the hepatoprotective activity of tea polyphenols (TP) and its relation with cytochrome P450 (CYP450) expression in mice.