Open AccessTransforming growth factor-β1 induces intestinal myofibroblast differentiation and modulates their migration
Author(s) -
Julia Brenmoehl,
Sandra N. Miller,
Claudia Hofmann,
Daniela Vogl,
Werner Falk,
Jürgen Schölmerich,
Gerhard Rogler
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.1431
Subject(s) - fibronectin , transforming growth factor beta , myofibroblast , transforming growth factor , cell migration , tgf beta signaling pathway , phosphorylation , microbiology and biotechnology , focal adhesion , tgf beta 1 , chemistry , biology , endocrinology , medicine , in vitro , extracellular matrix , biochemistry , fibrosis
To investigate the effects of transforming growth factor beta 1 (TGF-beta 1) on the differentiation of colonic lamina propria fibroblasts (CLPF) into myofibroblasts in vitro.