Open AccessNodular liver lesions involving multiple myeloma: A case report and literature review
Author(s) -
Xiaoning Wu,
Xinyan Zhao,
Jidong Jia
Publication year - 2009
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.15.1014
Subject(s) - medicine , multiple myeloma , immunofixation , pathology , bence jones protein , bone marrow , plasmacytoma , biopsy , beta 2 microglobulin , serum protein electrophoresis , immunoglobulin light chain , monoclonal , antibody , monoclonal antibody , immunology
We report a case of a 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in a regular medical examination. Routine laboratory tests were normal. PET-CT showed multiple bone lesions and nodular liver lesions. Liver biopsy revealed nodular infiltration of multiple myeloma with positive staining of kappa light chain. Further investigation of bone marrow aspiration, immunofixation and immunoelectrophoresis of serum protein, urine test for Bence-Jones protein, beta(2)-microglobulin in serum and urine confirmed the diagnosis. The patient also coinfected with hepatitis C virus (HCV). With six cycles of chemotherapy with VAD schedule, she achieved complete remission. In this report, a literature review of liver lesions involving multiple myeloma is also provided.