Open AccessPeutz-Jeghers syndrome with small intestinal malignancy and cervical carcinoma
Author(s) -
Lianjie Li,
Zhiqiang Wang,
Baoping Wu
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.7397
Subject(s) - peutz–jeghers syndrome , medicine , adenosquamous carcinoma , adenocarcinoma , polypectomy , malignancy , cervical cancer , pathological , stk11 , carcinoma , mucinous carcinoma , colorectal cancer , gastroenterology , cancer , pathology , colonoscopy , oncology , kras
We report a case of 30-year-old woman with Peutz-Jeghers syndrome (PJS). Because of small intestinal obstruction, she received the small intestinal polypectomy in 2001, and the pathological diagnosis was Peutz-Jeghers polyp canceration (mucinous adenocarcinoma, infiltrating full-thickness of the intestine). The patient did not feel uncomfortable after 6 mo of chemotherapy and other management. We kept a follow-up study on her and found that she suffered from cervical cancer in 2007, with a pathological diagnosis of cervical adenosquamous carcinoma.The patient presented with typical features of PJS, but without a family history. The PJS accompanied with both small intestinal and cervical malignancies has not been reported so far in the world.