Open AccessDisruption of colonic barrier function and induction of mediator release by strains of Campylobacter jejuni that invade epithelial cells
Author(s) -
Johannes Beltinger,
Jo del Buono,
M. M. Skelly,
John P. Thornley,
Robin C. Spiller,
W. A. Stack,
Christopher J. Hawkey
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.7345
Subject(s) - campylobacter jejuni , microbiology and biotechnology , lactate dehydrogenase , barrier function , tight junction , biology , ussing chamber , biochemistry , bacteria , secretion , enzyme , genetics
To study the mechanisms by which Campylobacter jejuni (C. jejuni) causes inflammation and diarrhea. In particular, direct interactions with intestinal epithelial cells and effects on barrier function are poorly under-stood.