Open AccessUndifferentiated embryonal sarcoma of liver in an old female: Case report and review of the literature
Author(s) -
Li Ma,
Yueping Liu,
Cui-Zhi Geng,
Zhi-Hui Tian,
Guoxiang Wu,
Xiaoling Wang
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.7267
Subject(s) - vimentin , cd68 , pathology , embryonal rhabdomyosarcoma , immunohistochemistry , sarcoma , hyaline , medicine , histology , hepatectomy , resection , rhabdomyosarcoma , surgery
The clinical characteristics of undifferentiated (embryonal) sarcoma of the liver (UESL) were investigated and the best treatment modalities were recommended. Both histology and immuno-histochemistry demonstrated the cellular features of this peculiar tumor. The tumor size was 12 cm multiply 9 cm multiply 8 cm in the right liver lobe. The patient underwent surgical resection of the tumor. The postoperative recovery was uneventful and she died eight months after diagnosis. The tumor showed mixed spindle and polygonal cells within the myxoid matrix. Some tumor cells contained eosinophilic hyaline globules that were positive for resistant diastase. Immunohistochemistry showed positive vimentin. Stellate and spindle cells were positively stained with alpha-1-antichymotrypsin (AACT) and CD68. This case indicates that UESL is not obviously differentiated in old-aged adults.