Open AccessFailure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver
Author(s) -
Samuel Wyllie,
Neal R. Barshes,
Feng Gao,
Saul J. Karpen,
John A. Goss
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6808
Subject(s) - ex vivo , ischemia , perfusion , liver injury , p selectin , reperfusion injury , blockade , in vivo , medicine , endocrinology , antibody , viaspan , cold storage , immunology , pharmacology , biology , platelet , receptor , microbiology and biotechnology , platelet activation , horticulture
To determine if blockade of P-selectin in the isolated blood-perfused cold ex vivo rat liver model protects the liver from ischemia-reperfusion injury.