Inhibitory effect of interferon-α-2b on expression of cyclooxygenase-2 and vascular endothelial growth factor in human hepatocellular carcinoma inoculated in nude mice | Zendy

Bin Cao | Zendy; Xiaoping Chen | Zendy; Peng Zhu | Zendy; Lei Ding | Zendy; Jian Guan | Zendy; Zuo-Liang Shi | Zendy

Open Access

Inhibitory effect of interferon-α-2b on expression of cyclooxygenase-2 and vascular endothelial growth factor in human hepatocellular carcinoma inoculated in nude mice

Author(s) -

Bin Cao,

Xiaoping Chen,

Peng Zhu,

Lei Ding,

Jian Guan,

Zuo-Liang Shi

Publication year - 2008

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.14.6802

Subject(s) - hepatocellular carcinoma , vascular endothelial growth factor , angiogenesis , apoptosis , tunel assay , alpha interferon , western blot , nude mouse , immunohistochemistry , medicine , alpha (finance) , cyclooxygenase , interferon , endocrinology , biology , immunology , vegf receptors , cancer , enzyme , gene , biochemistry , construct validity , nursing , patient satisfaction

To evaluate the effects of interferon-alpha-2b (IFN-alpha-2b) on expression of cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) in human hepatocellular carcinoma (HCC) inoculated in nude mice and to study the underlying mechanism of IFN-alpha-2b against HCC growth.

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