Open AccessAlbumin liver dialysis as pregnancy-saving procedure in cholestatic liver disease and intractable pruritus
Author(s) -
Maud Lemoine,
Aurélie Revaux,
Claire Francoz,
Guillaume Ducarme,
Sabine Bréchignac,
Emmanuel Jacquemin,
M. Uzan,
Nathalie Ganne-Carrié
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6572
Subject(s) - medicine , cholestasis , cholestasis of pregnancy , pregnancy , albumin , dialysis , liver disease , gastroenterology , disease , fetus , biology , genetics
Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating System (MARS) has been reported to reverse severe cholestasis-linked pruritus. Here, we report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus.