Open AccessLeptin transiently antagonizes ghrelin and long-lastingly orexin in regulation of Ca2+ signaling in neuropeptide Y neurons of the arcuate nucleus
Author(s) -
Daisuke Kohno,
Shigetomo Suyama,
Toshihiko Yada
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6347
Subject(s) - leptin , endocrinology , medicine , neuropeptide y receptor , ghrelin , arcuate nucleus , orexin , neuropeptide , arc (geometry) , orexin a , chemistry , energy homeostasis , hypothalamus , biology , hormone , receptor , obesity , geometry , mathematics
To explore the mechanism for interactions of leptin with ghrelin and orexin in the arcuate nucleus (ARC) activating neuropeptide Y (NPY) neurons during physiological regulation of feeding.