Open AccessImmunogenicity and immunoprotection of recombinant PEB1 in Campylobacter-jejuni -infected mice
Author(s) -
Lanying Du,
Zhenjiang Li,
Xiang D. Tang,
Junqiong Huang,
Weibo Sun
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6244
Subject(s) - recombinant dna , campylobacter jejuni , biology , immunogenicity , microbiology and biotechnology , xhoi , virology , plasmid , antibody , subcloning , antigenicity , gene , bamhi , immunology , bacteria , biochemistry , genetics
To construct a prokaryotic expression vector carrying Campylobacter jejuni peb1A gene and express it in Escherichia coli. Immunoreactivity and antigenicity of rPEB1 were evaluated. The ability of rPEB1 to induce antibody responses and protective efficacy was identified.