Open AccessBcl-2 expression significantly correlates with thymidylate synthase expression in colorectal cancer patients
Author(s) -
Riyad Bendardaf,
Raija Ristamäki,
Karí Syrjänen,
Seppo Pyrhönen
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6218
Subject(s) - thymidylate synthase , colorectal cancer , irinotecan , immunohistochemistry , medicine , fluorouracil , oncology , stage (stratigraphy) , cancer , metastasis , gastroenterology , biology , paleontology
To examine the expression of thymidylate synthase (TS) and oncoprotein Bcl-2 in advanced colorectal cancer (CRC) patients, and to determine their mutual relationship, association to therapeutic response and impact on disease outcome.