Open AccessA unique case of collagenous colitis presenting as protein-losing enteropathy successfully treated with prednisolone
Author(s) -
Soichi Sano,
Keiko Yamagami,
Ayako Tanaka,
Minako Nishio,
Tomoyuki Nakamura,
Yuki Kubo,
Takeshi Inoue,
Wataru Ueda,
Kenji Okawa,
Katsunobu Yoshioka
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6083
Subject(s) - hypoproteinemia , protein losing enteropathy , collagenous colitis , medicine , prednisolone , gastroenterology , enteropathy , colitis , colonoscopy , diarrhea , inflammatory bowel disease , ascending colon , differential diagnosis , pathology , disease , colorectal cancer , cancer
A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99mTc-human serum albumin scintigraphy. Collagenous colitis associated with protein-losing enteropathy (PLE) without small bowel disease was diagnosed. Prednisolone treatment ameliorated diarrhea and hypoproteinemia. Collagenous colitis should be included in the differential diagnosis of chronic diarrhea with hypoproteinemia for appropriate management.