Open AccessFibrinogen-like protein 2/fibroleukin prothrombinase contributes to tumor hypercoagulability via IL-2 and IFN-γ
Author(s) -
Kai Su,
Fang Chen,
Weiming Yan,
Qingtao Zeng,
Li Xu,
Dong Xi,
Bin Pi,
Xiaoping Luo,
Qin Ning
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.5980
Subject(s) - angiogenesis , cancer research , metastasis , medicine , cytokine , biology , pathology , cancer , immunology
To examine the role of Fibrinogen-like protein 2 (fgl2)/fibroleukin in tumor development. Fgl2 has been reported to play a vital role in the pathogenesis in MHV-3 (mouse hepatitis virus) induced fulminant and severe hepatitis, spontaneous abortion, allo- and xeno- graft rejection by mediating "immune coagulation".