Open AccessDepletion of CD4+CD25+ regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma
Author(s) -
Yi Ling Chen,
Jung Hua Fang,
Ming Deng Lai,
Yan Shen Shan
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.5797
Subject(s) - foxp3 , il 2 receptor , lymph , flow cytometry , cancer research , immunology , biology , immunity , microbiology and biotechnology , chemistry , immune system , pathology , t cell , medicine
To elucidate the distribution of CD4(+)CD25(+) regulatory T cells (Tregs) in different lymphoid tissues and its local enhancement on tumor growth before and after depletion of CD4(+)CD25(+) Tregs.