Open AccessCO liberated from CORM-2 modulates the inflammatory response in the liver of thermally injured mice
Author(s) -
Bo Sun,
Yan Sun,
Zhiwei Sun,
Xi Chen
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.547
Subject(s) - tumor necrosis factor alpha , liver injury , h&e stain , corm , nitric oxide , nitric oxide synthase , chemistry , endocrinology , medicine , in vivo , inflammation , pathology , biology , immunohistochemistry , microbiology and biotechnology , agronomy
To explore the effects of CO-releasing molecules [tricarbonyldichlororuthenium (II) dimer, CORM-2]-liberated CO on attenuation of inflammatory responses in liver of an experimental animal model of thermal injury and to investigate the associated potential mechanisms.