Open AccessDendroaspis natriuretic peptide relaxes gastric antral circular smooth muscle of guinea-pig through the cGMP/cGMP-dependent protein kinase pathway
Author(s) -
Can Cheng,
Zhengxu Cai,
Xinyi Gu,
Ling Shan,
Yong-Xiao Wang,
XianHong Yin,
Qing-Hui Qi,
Huishu Guo
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.5461
Subject(s) - guinea pig , protein kinase a , medicine , endocrinology , patch clamp , chemistry , cgmp dependent protein kinase , antrum , contraction (grammar) , muscle relaxation , smooth muscle tissue , nitric oxide , stomach , biology , kinase , smooth muscle , electrophysiology , biochemistry , cyclin dependent kinase 2
To systematically investigate if cGMP/cGMP-dependent protein kinase G (PKG) signaling pathway may participate in dendroaspis natriuretic peptide (DNP)-induced relaxation of gastric circular smooth muscle.