Open AccessPhosphatidylinositol 3-kinase/Akt pathway regulates hepatic stellate cell apoptosis
Author(s) -
Yan Wang,
Xiaoyu Jiang,
Li Liu,
HuiQing Jiang
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.5186
Subject(s) - protein kinase b , apoptosis , microbiology and biotechnology , biology , propidium iodide , pi3k/akt/mtor pathway , phosphatidylinositol , hepatic stellate cell , annexin , signal transduction , western blot , flow cytometry , programmed cell death , endocrinology , biochemistry , gene
To investigate the role of phosphatidylinositol 3-kinase (PI 3-K)/Akt signaling pathway in the balance of HSC activation and apoptosis in rat hepatic stellate cells (HSC).