Open AccessMechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma
Author(s) -
Yujia Gao,
Yan Xin,
Jianjun Zhang,
Jin Zhang
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.5000
Subject(s) - methylation , dna methylation , carcinogenesis , biology , gene expression , microbiology and biotechnology , cancer , cancer research , medicine , gene , genetics
To investigate the aberrant methylation of CHFR promoter in human gastric cancer (GC) and its impact on the expression of CHFR mRNA and protein, as well as its correlation with clinical and histological features of human GC.