Open AccessCoexistence of small cell neuroendocrine carcinoma and villous adenoma in the ampulla of Vater
Author(s) -
Jihong Sun,
M. Chao,
Shizheng Zhang,
Guangqiang Zhang,
Bin Li,
Jianjun Wu
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.4709
Subject(s) - ampulla of vater , adenocarcinoma , histogenesis , ampulla , pathology , adenoma , carcinoma , villous adenoma , medicine , cancer , immunohistochemistry
Small cell neuroendocrine carcinoma of the ampulla of Vater is extremely rare and different from the common ampullary adenocarcinoma. The ampullary adenoma is also a rare neoplasm and has the potential to develop an adenocarcinoma. Their coexistence has been rarely reported in the literature. We herein describe an unusual case of a small cell neuroendocrine carcinoma associated with a villous adenoma in the ampulla of Vater with emphasis on computed tomography (CT) and histopathological findings. We also discuss their clinical, histopathological and radiological features as well as possible histogenesis.