Open AccessLentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocellular carcinoma
Author(s) -
Qun Wang,
Quanyan Liu,
Zhisu Liu,
Qun Qian,
Qiang Sun,
Dingyu Pan
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.4633
Subject(s) - apoptosis , transfection , cell growth , flow cytometry , cyclin d1 , small hairpin rna , microbiology and biotechnology , cell cycle , cancer research , hepatocellular carcinoma , biology , rna interference , mtt assay , cyclin e , viability assay , cell culture , gene knockdown , rna , gene , biochemistry , genetics
To investigate the effects of lentivirus vector mediated short hairpin RNA interference targeting methionine adenosyltransferase 2beta gene (LV-shMAT2B) on hepatocelluar carcinoma (HCC) cells.