Open AccessCerebral venous thrombosis and heparin-induced thrombocytopenia in an 18-year old male with severe ulcerative colitis
Author(s) -
Gudrun Scheving Thorsteinsson,
Maria Magnussson,
Lena Hallberg,
Nils Wahlgren,
Fredrik Lindgren,
Petter Malmborg,
Thomas Casswall
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.4576
Subject(s) - medicine , ulcerative colitis , fondaparinux , heparin induced thrombocytopenia , venous thrombosis , inflammatory bowel disease , gastroenterology , heparin , thrombosis , venous thromboembolism , surgery , disease
The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescent boy who developed a cerebral sinus venous thrombosis during a relapse of his ulcerative colitis and who, while on treatment with heparin, developed heparin-induced thrombocytopenia (HIT). The treatment was then switched to fondaparinux, a synthetic and selective inhibitor of activated factor X.