Open AccessAssociation between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population: Role of serine protease inhibitor Kazal 1type and alcohol
Author(s) -
Venkata Muddana,
Janette Lamb,
Julia B. Greer,
Beth Elinoff,
Robert H. Hawes,
Peter B. Cotton,
Michelle A. Anderson,
Randall E. Brand,
Adam Slivka,
David C. Whitcomb
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.4486
Subject(s) - pancreatitis , medicine , single nucleotide polymorphism , exon , genotype , endocrinology , calcium sensing receptor , population , gastroenterology , biology , genetics , gene , calcium , calcium metabolism , environmental health
To test the hypothesis that calcium sensing receptor (CASR) polymorphisms are associated with chronic pancreatitis (CP), and to determine whether serine protease inhibitor Kazal 1type (SPINK1) N34S or alcohol are necessary co-factors in its etiology.