Open AccessIncreased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump
Author(s) -
Yvonne Meier,
Tina Zodan,
Carmen Lang,
Roland Zimmermann,
Gerd A. KullakUblick,
Peter J. Meier,
Bruno Stieger,
Christiane PauliMagnus
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.38
Subject(s) - cholestasis of pregnancy , cholestasis , medicine , genotype , bile acid , gastroenterology , bile salt export pump , allele , endocrinology , biology , pregnancy , genetics , fetus , transporter , gene
To study the association of three common ABCB11 and ABCC2 polymorphisms (ABCB11: 1331T>C --> V444A; ABCC2: 3563T>A --> V1188E and 4544G>A --> C1515Y) with intrahepatic cholestasis of pregnancy (ICP) and contraceptive-induced cholestasis (CIC).