Open AccessProtective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice
Author(s) -
Ping-Guo Liu,
Song He,
Yan-Hong Zhang,
Jian Wu
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2832
Subject(s) - apocynin , allopurinol , superoxide , xanthine oxidase , nadph oxidase , chemistry , pharmacology , reperfusion injury , xanthine oxidase inhibitor , liver injury , oxidative stress , endocrinology , ischemia , medicine , biochemistry , enzyme
To determine the effects of allopurinol, an inhibitor of xanthine oxidase, and apocynin, an inhibitor of NADPH oxidase, on oxidant stress and liver injury caused by hepatic ischemia/reperfusion (I/R) procedure in mice.
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