Open AccessPseudomonas exotoxin antisense RNA selectively kills hepatitis B virus infected cells
Author(s) -
Peter Hafkemeyer,
Ulrich Brinkmann,
Elizabeth Brinkmann,
Ira Pastan,
Hubert E. Blum,
Thomas F. Baumert
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2810
Subject(s) - biology , virology , pseudomonas exotoxin , antisense rna , rna , microbiology and biotechnology , complementary dna , reverse transcriptase , retrovirus , virus , reporter gene , gene , gene expression , recombinant dna , biochemistry
To present an approach for selectively killing retrovirus-infected cells that combines the toxicity of Pseudomonas exotoxin (PE) and the presence of reverse transcriptase (RT) in infected cells.