Open AccessConcomitant autoimmune and genetic pancreatitis leads to severe inflammatory conditions
Author(s) -
Jean Louis Frossard,
JeanMarc Dumonceau,
Catherine M. Pastor,
Laurent Spahr,
Antoine Hadengue
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2596
Subject(s) - pancreatitis , autoimmune pancreatitis , concomitant , medicine , mutation , hereditary pancreatitis , pancreatitis, chronic , gastroenterology , immunology , gene , biology , genetics , trypsinogen , enzyme , trypsin , biochemistry
Chronic pancreatitis characterized by an early onset should be extensively investigated including the search for a mutation of the PRSS1, SPINK-1 or CFTR genes and potential features of autoimmune pancreatitis. We here describe a case of chronic pancreatitis with an onset at a very young age in which a mutation of the PRSS1 and several features of autoimmune pancreatitis were identified.