Open AccessAnti-inflammatory activity of probiotic Bifidobacterium: Enhancement of IL-10 production in peripheral blood mononuclear cells from ulcerative colitis patients and inhibition of IL-8 secretion in HT-29 cells
Author(s) -
Akemi Imaoka,
Tatsuichiro Shima,
Kimitoshi Kato,
Shigeaki Mizuno,
Toshiki Uehara,
Satoshi Matsumoto,
Hiromi Setoyama,
Takeo Hara,
Yoshinori Umesaki
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2511
Subject(s) - bifidobacterium breve , probiotic , bifidobacterium bifidum , bifidobacterium , peripheral blood mononuclear cell , ulcerative colitis , bifidobacterium longum , secretion , microbiology and biotechnology , tumor necrosis factor alpha , colitis , immunology , biology , bacteria , medicine , in vitro , lactobacillus , endocrinology , biochemistry , genetics , disease
To determine the anti-inflammatory activity of probiotic Bifidobacteria in Bifidobacteria-fermented milk (BFM) which is effective against active ulcerative colitis (UC) and exacerbations of UC, and to explore the immunoregulatory mechanisms.