Open AccessEffect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2
Author(s) -
Bo Zhang,
Changliang Wang,
Wenhua Zhao,
Ming Lv,
Chunying Wang,
Weixia Zhong,
Wuyuan Zhou,
Wei Yu,
Yan Zhang,
Sheng Li
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2494
Subject(s) - apoptosis , pancreatic cancer , cell growth , nude mouse , cell culture , transplantation , mtt assay , cancer research , chemistry , cancer , microbiology and biotechnology , medicine , biology , biochemistry , genetics
To study the effect of 5-lipoxygenase/cyclooxygenase-2 (5-LOX/COX-2) dual inhibitor 7-tert-butyl-2, 3-dihydro-3, 3-dimethyl substituted dihydrofuran 30 (DHDMBF30) on proliferation and apoptosis of the pancreatic cancer cell line Capan-2 and the effect of DHDMBF30 on human pancreatic cancer in a nude mouse model.