Open AccessEffects of estradiol and progesterone on the proinflammatory cytokine production by mononuclear cells from patients with chronic hepatitis C
Author(s) -
Ying Yuan,
Ichiro Shimizu,
Mi Shen,
Eriko Aoyagi,
Hidetaka Takenaka,
Tatuzo Itagaki,
Mari Urata,
Katsutaka Sannomiya,
Nao Kohno,
Katsuyoshi Tamaki,
Masayuki Shono,
Tetsuji Takayama
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2200
Subject(s) - peripheral blood mononuclear cell , proinflammatory cytokine , cytokine , endocrinology , medicine , tumor necrosis factor alpha , oxidative stress , interleukin 6 , immunology , inflammation , biology , in vitro , biochemistry
To investigate the effects of estradiol (E2) and progesterone on the unstimulated and oxidative stress-stimulated production of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-8, and macrophage chemotactic protein (MCP)-1 by peripheral blood mononuclear cells (PBMCs) from patients with chronic hepatitis C and healthy controls.