Open AccessAnti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice
Author(s) -
Bhornprom Yoysungnoen,
Ponthip Wirachwong,
Chatchawan Changtam,
Apichart Suksamrarn,
Suthiluk Patumraj
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.2003
Subject(s) - curcumin , angiogenesis , hepatocellular carcinoma , in vivo , sorafenib , pharmacology , apoptosis , nude mouse , chemistry , vascularity , medicine , pathology , biology , biochemistry , microbiology and biotechnology
To determine the effect of tetrahydrocurcumin (THC) on tumor angiogenesis compared with curcumin (CUR) by using both in vitro and in vivo models of human hepatocellular carcinoma cell line (HepG2).