
Angiopoietin-1 targeted RNA interference suppresses angiogenesis and tumor growth of esophageal cancer
Author(s) -
Xiaohong Liu,
Chenguang Bai,
Yuan Yuan,
Daozhi Gong,
Shengdong Huang
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.1575
Subject(s) - transfection , apoptosis , angiogenesis , cell growth , microbiology and biotechnology , umbilical vein , cancer research , cell culture , rna interference , cd31 , small interfering rna , biology , chemistry , rna , gene , in vitro , biochemistry , genetics
To determine the inhibitory effect of the adenovirus-based angiopoietin-1 (Ang-1) targeted small interfering RNA expression system (Ad/Ang-1si) on the expression of the Ang-1 gene, cell growth and apoptosis in human esophageal cancer cell line Eca109.