Open AccessRegulatory T cells in patients with inflammatory bowel diseases treated with adacolumn granulocytapheresis
Author(s) -
Emilio Cuadrado,
Marta Alonso,
Montse Juan,
Pilar Echaniz,
Juan Arenas
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.1521
Subject(s) - foxp3 , medicine , il 2 receptor , inflammatory bowel disease , ulcerative colitis , immunology , flow cytometry , regulatory t cell , gastroenterology , disease , t cell , immune system
To investigate if the clinical efficacy of granulocytes and monocytes by adsorption (GMA) is associated with an increased frequency of peripheral regulatory T cells (Tregs), as these cells have proven to be successful in suppressing inflammatory bowel disease (IBD) in animal models.