Open AccessMK615 inhibits pancreatic cancer cell growth by dual inhibition of Aurora A and B kinases
Author(s) -
Toshie Okada,
Tokihiko Sawada,
Tatsushi Osawa,
Masakazu Adachi,
Keiichi Kubota
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.1378
Subject(s) - flow cytometry , microbiology and biotechnology , cell growth , lactate dehydrogenase , kinase , blot , cell culture , apoptosis , cell cycle , pancreatic cancer , in vitro , growth inhibition , aurora inhibitor , biology , cell counting , chemistry , cancer cell , cell , cancer , enzyme , biochemistry , genetics , gene
To investigate the anti-neoplastic effect of MK615, an anti-neoplastic compound isolated from Japanese apricot, against human pancreatic cancer cells in vitro.