Open AccessPilot project for screening cervical cancer using HPV testing
Author(s) -
И. Р. Минниахметов,
Maksim Zabelin,
Iliya Olkov,
Р. И. Хусаинова
Publication year - 2020
Publication title -
voprosy onkologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 11
eISSN - 2949-4915
pISSN - 0507-3758
DOI - 10.37469/0507-3758-2020-66-6-618-624
Subject(s) - hybrid capture , cervical cancer , medicine , viral load , dna testing , oncology , human papillomavirus , cervical cancer screening , cancer , gynecology , hpv infection , virology , cervical intraepithelial neoplasia , virus , biology , genetics
The results of a large-scale pilot project on HPV-testing by the Hybrid Capture technology (digene HC2 HPV DNA Test) of 28928 women in the Republic of Bashkortostan were summarized. The frequency of high-risk HPV infection in the studied region of Russia was 10.6%, the average viral load was 319.97 RLU / COV ratio in the total sample, which corresponds to a high viral load (more than 3x107 genomic equivalents). In 5.4% of HPV-positive women, cervical pathology was revealed, cervical cancer in the early stages was detected in 21 (0.69%) women (20 cancer in situ and 1 cancer IA).