Open AccessChemical composition and larvicidal activity of the essential oil of Pimenta dioica leaves
Author(s) -
Paulo Roberto Barros Gomes,
Silvio Carvalho Marinho,
Gustavo Oliveira Everton,
Eduardo Fonseca Silva,
Maria Alves Fontenele,
Wellington da Silva Lyra,
Adriana Crispim de Freitas,
Virlane Kelly Lima Hunaldo,
Rômicy Dermondes Souza,
Hilton Costa Louzeiro,
María Paula,
Jonas Batista Reis,
Andrea Vasconcelo Melo,
Victor Elias Mouchrek Filho
Publication year - 2022
Publication title -
boletín latinoamericano y del caribe de plantas medicinales y aromáticas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 21
ISSN - 0717-7917
DOI - 10.37360/blacpma.22.21.2.12
Subject(s) - eugenol , phenylpropanoid , essential oil , chemistry , aedes aegypti , gas chromatography–mass spectrometry , chemical composition , composition (language) , traditional medicine , botany , gas chromatography , chromatography , larva , biology , mass spectrometry , organic chemistry , medicine , linguistics , philosophy , biosynthesis , enzyme
In this study, we investigated the main constituent, the predominant class and biological activity of the essential oil extracted from the leaves of Pimenta dioica and the pattern of the major constituent against larvae in the third stage of Aedes aegypti. For this reason, we extracted the oil by hydrodistillation, identified its components by gas chromatography coupled with mass spectrometry (GC/MS) and calculated the lethal concentration (LC50) of the larvicidal activity using the Reed-Muench method. The results show that the oil consists mainly of eugenol, in which the phenylpropanoid class predominated and the lethal concentration, LC50, was 38.86 μg mL-1at a confidence level of 2.25 μg mL-1, while the eugenol standard presented LC5079.75 μg mL-1at a confidence level of 2.10 μg mL-1. Given the facts, we conclude that the oil is more active than the standard and that it has the potential to replace chemical larvicides.