Open AccessModern approaches to the treatment of radioiodine-refractory differentiated thyroid cancer
Author(s) -
Д.О. Джужа,
Станіслав Дмитрович Мясоєдов
Publication year - 2021
Publication title -
radiation diagnostics, radiation therapy
Language(s) - English
Resource type - Journals
eISSN - 2707-0700
pISSN - 2707-0697
DOI - 10.37336/2707-0700-2021-1-4
Subject(s) - thyroid cancer , medicine , refractory (planetary science) , radioiodine therapy , tyrosine kinase , oncology , cancer research , thyroid , targeted therapy , cancer , biology , receptor , astrobiology
Radioiodine therapy is the main post-operation method of treatment of advanced differentiated thyroid cancer, but the loss of ability of iodine uptake causes the poor prognosis. The follow-up of patients with radioiodine-refractory differentiated thyroid cancer (RRDTC) is a serious problem. In review the definition, genesis, diagnostics and treatment of RRDTC were revealed. Taking into account the ineffectiveness of traditional methods of redifferentiation therapy, the perspectives of administration of targeted therapies with tyrosine kinase inhibitors were showed. Key words: radioiodine-refractory differentiated thyroid cancer, radioiodine therapy, targeted therapies with tyrosine kinase inhibitors.