Open AccessSEROPREVALENCE OF ANTI-MEASLES IGG IN THE POPULATION OF KHARKIV REGION IN 2018-2019
Author(s) -
I. P. Yudin,
Irina Kuchma,
Andriy Voliansky
Publication year - 2019
Publication title -
ìmunologìâ ta alergologìâ: nauka ì praktika
Language(s) - English
Resource type - Journals
ISSN - 2707-1871
DOI - 10.37321/immunology.2019.04-03
Subject(s) - seroprevalence , herd immunity , measles , medicine , vaccination , population , herd , immunity , immunology , serology , antibody , demography , veterinary medicine , environmental health , immune system , sociology
Aim. The aim of this study was to evaluate herd immunity against measles in different age groups of the Kharkiv region of Ukraine’s population.
Materials and methods. Seroprevalence of specific IgG antibodies was studied among different age groups of the Kharkiv region population from February 2018 to July 2019 by ELISA method.
Results. A number of 6564 sera samples were processed. The overall seropositivity level was 91.3%; negative results were 5.3% and 3.3% equivocal. The highest seropositivity for IgG (> 98%) was in people aged 50 years and older. The lowest seropositivity rates were observed in the cohorts of 20-29 years (87.2%), 30-39 years (86.9%), and 40-49 years (91.1%).
Conclusions. Measles-susceptible populations were identified for which new prevention strategies should be applied in the form of personalized vaccination campaigns to increase herd immunity.